Ingredient Spotlight: Titanium Dioxide - Is It Safe?

Ingredient Spotlight: Titanium Dioxide - Is It Safe?

Posted by Angela Gross - Naturally Safe Cosmetics Australia on 19th May 2019

Controversy surrounding the use of Titanium Dioxide as an ingredient in everyday products has been around for years but, in recent weeks, this mineral has found itself back in the spotlight with questions being raised, yet again, about its safety.

So, what is Titanium Dioxide?

Titanium Dioxide (TiO2) is an inorganic compound. It is a naturally occurring oxide of Titanium. Its appearance is that of a fine, white powder. It is used as a brightening and whitening agent in both industrial and consumer products. It can be found in everything from paints, plastics and adhesives to textiles, floor coverings and ceramics. It is also used as a whitening (and anti-caking) agent in many everyday foods. Many cosmetics also contain TiO2, as do many sunscreens and other personal care items like toothpaste.

What purpose does Titanium Dioxide serve in cosmetics and sunscreens?

Titanium Dioxide provides protection from both UVA and UVB rays. That’s why it's a popular choice in sunscreen products and also many mineral foundations, which are often labelled 'SPF15' or 'SPF20'. TiO2 can improve makeup's ability to provide good coverage and is also known to be gentle and non-irritating, making it a good option for sunscreen, especially as chemical UV absorbers, like Oxybenzone, are often irritating to people with sensitive skin and babies.

Avoid spray on sunscreens with Titanium Dioxide. Image credit: Canva

Is Titanium Dioxide safe?

Opinion seems to be divided on whether TiO2 is a safe ingredient for use in products used by humans. Some scientists claim it is safe, while others claim it is a carcinogen. Whilst some studies have shown that exposure to Titanium Dioxide dust by rats caused respiratory tract cancer in those rats, there does not appear to be any evidence or scientific data to support the claim that TiO2 causes cancer in humans.

As with many things, it’s not a simple ‘black and white’ case. When considering the safety of TiO2, one needs to consider its safety in terms of human consumption (i.e. actually putting it into your body through the consumption of foods containing it and brushing your teeth with toothpaste that includes it) versus using it on the outside of your body, as you would with cosmetics and sunscreen.

Here are a few things to consider:

  • The International Agency for Research on Cancer (IARC) classifies Titanium Dioxide as a Group 2B carcinogen, which means it's "possibly carcinogenic to humans."
  • In terms of food consumption, the US Food and Drug Administration has classified TiO2 as “Generally Recognized as Safe” (GRAS).
  • The EWG’s Skin Deep Cosmetics Database rates it a 3, which places it at the lowest end of moderately hazardous ingredients.
  • In terms of sunscreens, which often use nano-sized TiO2 (see below), Australia’s Therapeutic Good Administration has stated that “there is no in vivo evidence to indicate possible toxicity of nanoparticulate TiO2 in people using sunscreens” and that “to date, the current weight of evidence indicates the particles remain on the surface of the skin and in the outer dead layer (stratum corneum) of the skin.”
  • In 2015, after 2 years of class action litigation involving over 100 cosmetic companies, a California court determined that dangerous exposure claims concerning TiO2 lacked merit and concluded that testing performed in connection with the lawsuit showed that “the titanium dioxide used in cosmetics is processed with other ingredients that will adhere to the titanium dioxide, such as colorants and other ingredients, so that the particles become too large to be of concern.”

So, generally speaking, TiO2 appears to be a low safety hazard, however, there are two things to take into consideration:

1.    How fine the powder particles are; and

2.    How the powder is used.

Micronisation versus Nanoparticles

Titanium Dioxide can come in two forms: nano (or nanoparticle) and non-nano. Nanoparticles measure between 1 and 100 nanometres in size. (By the way, 1 nanometre = one billionth of a metre!) The advantage of nanoparticles when it comes to TiO2 is that they prevent white streaks or a white cast to the skin which can happen when products containing TiO2, like sunscreen, are applied to the skin. This is why many sunscreens containing TiO2 use nanoparticles. The same often applies to Zinc Oxide. Apparently looking a bit white when you apply sunscreen is not popular with consumers, so companies use nanoparticles to create sunscreens that go on clear.

Most natural makeup brands use micronized TiO2. This means it is made into very fine particles but is not nano-sized. In addition to being micronized, the TiO2 particles are also coated with substances like alumina, dimethicone, silica, and trimethoxycaprylsilane, which improves application, improves the cosmetic ‘elegance’ of products and provides better sun protection. It is believed that micronised Titanitum Dioxide doesn’t penetrate healthy, unbroken skin, so there is no risk of it entering the body via the skin. It is also thought that, even when nanoparticle TiO2 is used, the molecular size of the substance used to coat it is large enough to also prevent the nanoparticles from penetrating beyond the uppermost layers of skin, as per the 2015 California court case.

Titanium Dioxide is a popular ingredient in mineral makeup. Image credit: iStock

What's the biggest concern?

The main concern with TiO2 appears to be inhalation of airborne particles. Inhalation concerns apply to products that may be aerosolized, like loose (and pressed) powder makeup products and spray-on sunscreens. The use of non-nano TiO2 in rub-on sunscreens and in liquid or cream cosmetics, like foundations for example, does not appear to be of concern.

So what can we conclude from all of this?

I am in no way an expert or authority on Titanium Dioxide, its safety or otherwise. This article is merely intended to offer a little insight into this topic, especially as it is currently in the media once again. The main points to take away are:

1.  There doesn't appear to be any conclusive evidence that Titanium Dioxide causes cancer in humans.

2.  The biggest concern appears to be inhalation.

3.  Many foods contain TiO2, including lollies, chewing gum, nut spreads, energy drinks, dairy products, processed deli meats, canned fish products, processed snacks, oral supplements and more. If you’re concerned, check the ingredients listing for Pigment White 6 (PW6), E171 or CI 77891.

4.  When it comes to oral care, toothpaste (which may also be ingested) also often contains TiO2.

5. For sunscreens, avoid spray-on or aerosolised sunscreens, regardless of whether or not they contain nanoparticles.

6.  For cosmetics, choose makeup brands that don’t use nanoparticles and take care not to inhale the product when using powdered makeup (loose or pressed). This is just common sense anyway – you should never inhale any powdered product whether food, cosmetics or otherwise.

Finally, there’s a lot of information to be found online regarding Titanium Dioxide. If you are concerned about your exposure to this ingredient, then I urge you to do your own research and make up your own mind.

ReferencesEWG Skin Deep Cosmetic Database; chemicalsafetyfacts.org; paulaschoice.com.au; reefrepair.org; mercola.com

Note: The author and Naturally Safe Cosmetics are not health professionals. Any information or advice in this article is of a general nature only and may include the author's own personal opinion. Nothing in this article is intended to diagnose, treat, cure or prevent any disease. For medical advice regarding your own personal circumstances, we recommend you contact your GP or other healthcare professional.